Healthcare Professionals
This page is intended for registered healthcare professionals considering Metabo Age™ as part of a structured metabolic wellness protocol. It summarises the published evidence base for each ingredient, presents key clinical data, and provides a direct channel for professional enquiries and account registration.
Metabo Age™ is a health supplement. It is not a medicine and is not intended to diagnose, treat, cure, or prevent any disease. Clinical data referenced below relates to individual ingredients as studied in published peer-reviewed trials, not to the Metabo Age formulation as a whole.
Key Ingredient Evidence
Data from Singh et al. (2022), Cell Reports Medicine. Double-blind, placebo-controlled RCT. n=88 healthy middle-aged adults (40–64 years). Duration: 4 months. Doses: 500mg/day and 1,000mg/day vs placebo.
Source: Singh A, et al. Cell Rep Med. 2022;3(5):100633. doi:10.1016/j.xcrm.2022.100633
Average peak torque improvement at 4 months. Hamstring and knee flexion measurements.
Illustrative trajectory based on published trial data. Endurance measured by isometric fatigue testing.
Skeletal muscle biopsies and plasma analysis. UA 500mg vs placebo at 4 months. Relative change from baseline.
Note: Biomarker data are illustrative of relative directional trends reported in Singh et al. (2022). Absolute values vary by biomarker. Refer to the original publication for full statistical analysis.
Formulation Rationale
Dose per Capsule
250 mg per capsule
Mechanism of Action
Urolithin A is a postbiotic metabolite produced by gut microbiota from ellagitannins found in pomegranate and berries. It is the only compound clinically demonstrated to activate mitophagy — the selective clearance of dysfunctional mitochondria — in human skeletal muscle. By promoting mitochondrial quality control, it supports the maintenance of cellular energy production capacity as the body ages.
Evidence Summary
Singh et al. (2022), Cell Reports Medicine. Double-blind, placebo-controlled RCT, n=88, ages 40–64, 4 months. 500mg/day: +12% hamstring strength, +10.6% knee flexion strength vs placebo. Significant improvements in mitochondrial gene expression biomarkers in skeletal muscle biopsies.
Primary Reference
Singh A, et al. Cell Rep Med. 2022;3(5):100633. doi:10.1016/j.xcrm.2022.100633
View on PubMed →Clinical Context
Urolithin A is the anchor ingredient in the Metabo Age formulation. Its clinical evidence base is the strongest of any mitophagy-activating compound in human supplementation.
| Ingredient | Amount per Serving | Primary Role | Key Reference |
|---|---|---|---|
| Urolithin A | 500 mg | Mitophagy activation, mitochondrial quality control | Singh et al., Cell Rep Med, 2022 |
| Alpha-Lipoic Acid | 700 mg | Mitochondrial cofactor, antioxidant support | Packer et al., Free Radic Biol Med, 1995 |
| Magnesium Glycinate | 200 mg | ATP synthesis cofactor, enzymatic support | Barbagallo & Dominguez, Mol Aspects Med, 2010 |
| Chromium Picolinate | 400 mcg | Insulin signalling, glucose metabolism support | Broadhurst & Domenico, Diabetes Technol Ther, 2006 |
Capsule shell: plant-derived (HPMC). No artificial colours, flavours, or preservatives. Suitable for vegetarians. Manufactured by FinLab. Store below 25°C, away from direct sunlight and moisture.
Professional Account
For clinic supply, patient recommendation accounts, wholesale pricing, or clinical protocol integration, please complete the form below. Our clinical team will respond within two business days.